Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825955 | 1.00 | LPAR1 (0.46) | LPAR1LPAR5 | |
| SCHEMBL8497528 | 1.00 | LPAR1 (0.46) | LPAR1LPAR5 | |
| SCHEMBL8497523 | 1.00 | LPAR1 (0.46) | LPAR1LPAR5 | |
| SCHEMBL4959388 | 0.91 | LPAR1 (0.51) | LPAR1LPAR5 | |
| SCHEMBL4959382 | 0.91 | LPAR1 (0.51) | LPAR1LPAR5 | |
| SCHEMBL8494932 | 0.91 | LPAR1 (0.51) | LPAR1LPAR5 | |
| SCHEMBL8493183 | 0.91 | LPAR1 (0.51) | LPAR1LPAR5 | |
| SCHEMBL9255423 | 0.91 | LPAR1 (0.51) | LPAR1LPAR5 | |
| SCHEMBL8493909 | 0.91 | LPAR1 (0.51) | LPAR1LPAR5 | |
| SCHEMBL8825925 | 0.91 | LPAR1 (0.51) | LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631401-A | Inhibitors of protein farnesyltransferase and squalene synthase | ABBOTT LABORATORIES (US) | 1997-05-20 | — | — | US | disclosed |
| WO-1995021815-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND SQUALENE SYNTHASE | ABBOTT LABORATORIES (US) | 1995-08-17 | — | — | WO | disclosed |