Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 6/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809155 | 1.00 | NPSR1 (0.41) | NPSR1FAAHMGLLPKMSMN1; SMN2 | |
| SCHEMBL9663985 | 0.90 | NPSR1 (0.35) | NPSR1FAAHMGLLSMN1; SMN2MEN1 | |
| SCHEMBL8825831 | 0.88 | NPSR1 (0.38) | NPSR1FAAHMGLLPKMSMN1; SMN2 | |
| SCHEMBL7806859 | 0.88 | NPSR1 (0.38) | NPSR1FAAHMGLLPKMSMN1; SMN2 | |
| SCHEMBL3898520 | 0.83 | USP2 (0.33) | CYP3A4ELANEADRB2ADRB1ADRB3 | |
| SCHEMBL3896668 | 0.83 | NPSR1 (0.34) | NPSR1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9222247 | 0.82 | PLA2G10 (0.40) | NPSR1ALDH1A1ELANE | |
| SCHEMBL9279337 | 0.82 | PLA2G10 (0.40) | NPSR1ALDH1A1ELANE | |
| SCHEMBL9273334 | 0.79 | TDP1 (0.39) | MEN1KMT2AALDH1A1ELANE | |
| SCHEMBL9223494 | 0.79 | TDP1 (0.39) | MEN1KMT2AALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703243-A | Intermediates for pyrrolidylthiocarbapenem derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-12-30 | — | — | US | disclosed |