Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 4/20 | 0.59 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826314 | 1.00 | FABP7 (0.59) | FABP7FABP5MMP2FFAR1FFAR4 | |
| SCHEMBL7761974 | 0.87 | FABP7 (0.49) | FABP7FABP5 | |
| SCHEMBL7760087 | 0.87 | FABP7 (0.49) | FABP7FABP5 | |
| SCHEMBL7761978 | 0.87 | FABP7 (0.49) | FABP7FABP5 | |
| SCHEMBL7760093 | 0.87 | FABP7 (0.49) | FABP7FABP5 | |
| SCHEMBL7757018 | 0.87 | FABP7 (0.73) | FABP7FABP5SMN1; SMN2 | |
| SCHEMBL7757006 | 0.87 | FABP7 (0.73) | FABP7FABP5SMN1; SMN2 | |
| SCHEMBL12114007 | 0.87 | FABP7 (0.73) | FABP7FABP5SMN1; SMN2 | |
| SCHEMBL13432587 | 0.87 | FABP7 (0.73) | FABP7FABP5SMN1; SMN2 | |
| SCHEMBL31509821 | 0.87 | FABP7 (0.73) | FABP7FABP5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631401-A | Inhibitors of protein farnesyltransferase and squalene synthase | ABBOTT LABORATORIES (US) | 1997-05-20 | — | — | US | disclosed |
| WO-1995021815-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND SQUALENE SYNTHASE | ABBOTT LABORATORIES (US) | 1995-08-17 | — | — | WO | disclosed |