Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19744070 | 0.93 | AKR1B1 (0.54) | AKR1B1MAOBTP53THRBSLC2A1 | |
| SCHEMBL9637038 | 0.92 | AKR1B1 (0.53) | AKR1B1MAOBTP53THRBSLC2A1 | |
| SCHEMBL8106216 | 0.91 | MAOB (0.52) | AKR1B1MAOBTP53THRBSLC2A1 | |
| SCHEMBL8123310 | 0.91 | AKR1B1 (0.62) | AKR1B1MAOBTP53THRBSLC2A1 | |
| SCHEMBL10358927 | 0.88 | MAPK1 (0.60) | AKR1B1MAOBTP53THRBSLC2A1 | |
| SCHEMBL8106509 | 0.88 | AKR1B1 (0.56) | AKR1B1MAOBTP53THRBSLC2A1 | |
| SCHEMBL22617428 | 0.86 | MAOB (0.61) | AKR1B1MAOBTP53THRBSLC2A1 | |
| SCHEMBL7633152 | 0.86 | AKR1B1 (0.59) | AKR1B1MAOBTP53THRBSLC2A1 | |
| SCHEMBL10358950 | 0.86 | MAOB (0.49) | AKR1B1MAOBTP53THRBSLC2A1 | |
| SCHEMBL4991500 | 0.85 | AKR1B1 (0.54) | AKR1B1MAOBTP53THRBSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |