Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037710 | 0.95 | TDP1 (0.47) | TDP1POLBMAPK1PGDABCB1 | |
| SCHEMBL4656048 | 0.95 | TDP1 (0.47) | TDP1POLBMAPK1PGDABCB1 | |
| SCHEMBL1290131 | 0.95 | TDP1 (0.47) | TDP1POLBMAPK1PGDABCB1 | |
| SCHEMBL3054750 | 0.89 | TDP1 (0.45) | TDP1POLBMAPK1PGD | |
| SCHEMBL3047380 | 0.89 | TDP1 (0.45) | TDP1POLBMAPK1PGD | |
| SCHEMBL3066072 | 0.89 | TDP1 (0.45) | TDP1POLBMAPK1ALDH1A1 | |
| SCHEMBL4604940 | 0.84 | TDP1 (0.50) | TDP1POLBMAPK1PGDABCB1 | |
| SCHEMBL4605823 | 0.83 | TDP1 (0.49) | TDP1POLBMAPK1PGDABCB1 | |
| SCHEMBL19065772 | 0.83 | TDP1 (0.49) | TDP1POLBMAPK1ABCB1ALDH1A1 | |
| SCHEMBL4606686 | 0.83 | TDP1 (0.49) | TDP1POLBMAPK1PGDABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213487-B | Preparation method of azacitidine | 安徽普利药业有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-114213487-A | Preparation method of azacitidine | 安徽普利药业有限公司 | 2022-03-22 | — | — | CN | disclosed |
| US-5668271-A | Indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| US-5591842-A | ANTICARCINOGENIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| US-5589365-A | ANTITUMOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0545195-B1 | Indolopyrrolocarbazole derivatives | BANYU PHARMA CO LTD (JP) | 1995-11-22 | — | — | EP | disclosed |
| EP-0545195-A1 | Indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4003995-A | Glycosyl esters of phenoxyisobutyric acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-01-18 | — | — | US | disclosed |