Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.69 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.69 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829475 | 1.00 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2PTGER4ALOX5LTB4R | |
| SCHEMBL8829472 | 1.00 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2PTGER4ALOX5LTB4R | |
| SCHEMBL8829375 | 0.93 | CYSLTR1 (0.80) | CYSLTR1CYSLTR2PTGER4LTB4R | |
| SCHEMBL8829374 | 0.93 | CYSLTR1 (0.80) | CYSLTR1CYSLTR2PTGER4LTB4R | |
| SCHEMBL8829409 | 0.93 | CYSLTR1 (0.80) | CYSLTR1CYSLTR2PTGER4LTB4R | |
| SCHEMBL8829393 | 0.92 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2PTGER4ALOX5LTB4R | |
| SCHEMBL8829397 | 0.92 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2PTGER4ALOX5LTB4R | |
| SCHEMBL8829406 | 0.92 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2PTGER4ALOX5LTB4R | |
| SCHEMBL9146513 | 0.89 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2PTGER4ALOX5CYP4F2 | |
| SCHEMBL8829399 | 0.89 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2PTGER4ALOX5CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404440-B1 | Substituted sulfonamides and related compounds in the treatment of asthma, arthritis, and related diseases | PFIZER (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0404440-A2 | Substituted sulfonamides and related compounds in the treatment of asthma, arthritis, and related diseases | PFIZER INC. (US) | 1990-12-27 | — | — | EP | disclosed |