SCHEMBL8830458

SCHEMBL8830458

CC(C)C1(Br)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1067381 0.65 MEN1 (0.31)
SCHEMBL17828432 0.65 MEN1 (0.31)
SCHEMBL17828433 0.58 MEN1 (0.50)
SCHEMBL16295072 0.58 MEN1 (0.62)
SCHEMBL7260823 0.58 MEN1 (0.62)
SCHEMBL554655 0.58 MEN1 (0.62)
Perfluorocyclobutane SCHEMBL24521 0.58 MEN1 (0.62)
SCHEMBL693244 0.58
SCHEMBL812362 0.58 MEN1 (0.62)
SCHEMBL61759 0.58 MEN1 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0606308-A1 FLUOROALKYLATED AMPHIPHILIC LIGANDS, THEIR METALLIC COMPLEXES AND THEIR USES ALLIANCE PHARMACEUTICAL CORP. (US) 1994-07-20 EP claimed
WO-1993007123-A1 FLUOROALKYLATED AMPHIPHILIC LIGANDS, THEIR METALLIC COMPLEXES AND THEIR USES S.A. A.T.T.A. APPLICATIONS ET TRANSFERTS DE TECHNOLOGIES AVANCEES (FR) 1993-04-15 WO claimed
US-5648362-A LIGANDS TRANSPORTABLE BY LIPOSOMES FOR COMPLEXES ALLIANCE PHARMACEUTICAL CORP. (US) 1997-07-15 US disclosed
US-5399694-A Antitumor APPLICATION ET TRANSFERTS DE TECHNOLOGIES AVANCEES (FR) 1995-03-21 US disclosed
EP-0606308-A1 FLUOROALKYLATED AMPHIPHILIC LIGANDS, THEIR METALLIC COMPLEXES AND THEIR USES ALLIANCE PHARMACEUTICAL CORP. (US) 1994-07-20 EP disclosed
WO-1993007123-A1 FLUOROALKYLATED AMPHIPHILIC LIGANDS, THEIR METALLIC COMPLEXES AND THEIR USES S.A. A.T.T.A. APPLICATIONS ET TRANSFERTS DE TECHNOLOGIES AVANCEES (FR) 1993-04-15 WO disclosed