Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 5/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878222 | 0.87 | IDO1 (0.36) | C1SIDO1PLATAXLCCR5 | |
| SCHEMBL10266425 | 0.86 | C1S (0.36) | C1SIDO1PLATAXLCCR5 | |
| SCHEMBL12730472 | 0.86 | IDO1 (0.35) | C1SIDO1PLATAXLTAAR1 | |
| SCHEMBL3431041 | 0.85 | C1S (0.35) | C1SIDO1PLATAXLCCR5 | |
| SCHEMBL3429413 | 0.85 | C1S (0.35) | C1SIDO1PLATAXLCCR5 | |
| SCHEMBL1654372 | 0.83 | AXL (0.35) | C1SIDO1PLATAXLTAAR1 | |
| SCHEMBL1688346 | 0.81 | NPC1 (0.36) | PLATAXLTAAR1RAB9ASMN1; SMN2 | |
| SCHEMBL2624059 | 0.77 | MAPK14 (0.33) | AXLRAB9ASMN1; SMN2APLNRDRD2 | |
| SCHEMBL2624052 | 0.77 | PIK3R2 (0.34) | RAB9ASMN1; SMN2APLNR | |
| SCHEMBL2624061 | 0.77 | PLAT (0.38) | PLATAXLTAAR1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040242-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |