Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830795 | 0.89 | POLB (0.42) | POLBSMN1; SMN2SSTR1SSTR4MEN1 | |
| SCHEMBL8830804 | 0.88 | POLB (0.41) | POLBSMN1; SMN2SSTR1SSTR4TSHR | |
| SCHEMBL8830761 | 0.86 | POLB (0.40) | POLBSMN1; SMN2SSTR1SSTR4MEN1 | |
| SCHEMBL8830841 | 0.78 | POLB (0.38) | POLBSMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL8830686 | 0.78 | MEN1 (0.36) | POLBSMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL8830938 | 0.77 | KDM4E (0.34) | POLBSMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL8830967 | 0.74 | PDCD1 (0.43) | SMN1; SMN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8830767 | 0.74 | NR1H4 (0.35) | MEN1KMT2A | |
| SCHEMBL2033491 | 0.74 | POLB (0.43) | POLBSMN1; SMN2SSTR1SSTR4MEN1 | |
| SCHEMBL8830666 | 0.74 | EPHX1 (0.36) | TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681979-A | Process for the producing of alkylcyclopentanone derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0731083-A1 | Process for the producing of alkylcyclopentanone derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-09-11 | — | — | EP | disclosed |