Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13975602 | 0.83 | LRRK2 (0.51) | LRRK2 | |
| SCHEMBL883235 | 0.77 | LRRK2 (0.54) | LRRK2 | |
| SCHEMBL382305 | 0.70 | LRRK2 (0.67) | LRRK2 | |
| SCHEMBL883298 | 0.70 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL13834221 | 0.69 | LRRK2 (0.53) | LRRK2 | |
| SCHEMBL883255 | 0.69 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL883317 | 0.69 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL883172 | 0.69 | LRRK2 (0.60) | LRRK2 | |
| SCHEMBL883597 | 0.68 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL883640 | 0.68 | LRRK2 (0.97) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038743-A1 | PYRAZOLOPYRIDINES AS INHIBITORS OF THE KINASE LRRK2 | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2012-03-29 | — | — | WO | disclosed |