Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15776522 | 1.00 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2USP2NR1H2RXRA | |
| SCHEMBL17654997 | 1.00 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2USP2NR1H2RXRA | |
| SCHEMBL17031882 | 0.89 | USP2 (0.38) | HSD17B10SMN1; SMN2USP2NR1H2RXRA | |
| SCHEMBL17036678 | 0.88 | HSD17B10 (0.37) | HSD17B10SMN1; SMN2USP2NR1H2RXRA | |
| SCHEMBL17654999 | 0.86 | USP2 (0.36) | HSD17B10SMN1; SMN2USP2CHRM2CHRM1 | |
| SCHEMBL15776514 | 0.86 | USP2 (0.36) | HSD17B10SMN1; SMN2USP2CHRM2CHRM1 | |
| SCHEMBL35211488 | 0.85 | HSD17B10 (0.40) | HSD17B10SMN1; SMN2USP2NR1H2CHRM2 | |
| SCHEMBL16369976 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2USP2NR1H2RXRA | |
| SCHEMBL905280 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2USP2NR1H2RXRA | |
| SCHEMBL905275 | 0.84 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2USP2NR1H2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |
| WO-2012040242-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |