Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.70 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.70 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.70 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.70 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.70 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055150 | 0.88 | HPGD (0.89) | KMT2AALDH1A1MEN1HDAC1HDAC8 | |
| SCHEMBL3821744 | 0.87 | F10 (0.93) | F10KMT2AALDH1A1MEN1HDAC1 | |
| SCHEMBL7249253 | 0.86 | F10 (0.69) | F10KMT2AALDH1A1MEN1HDAC1 | |
| SCHEMBL19472683 | 0.84 | GAA (0.70) | F10KMT2AALDH1A1MEN1POLB | |
| SCHEMBL6866814 | 0.84 | KMT2A (0.82) | F10KMT2AALDH1A1MEN1HDAC1 | |
| SCHEMBL5221640 | 0.84 | F10 (0.81) | F10KMT2AALDH1A1MEN1HDAC1 | |
| SCHEMBL9620772 | 0.84 | F10 (0.81) | F10KMT2AALDH1A1MEN1HDAC1 | |
| SCHEMBL29808279 | 0.83 | MEN1 (0.83) | KMT2AALDH1A1MEN1POLBHPGD | |
| SCHEMBL12077495 | 0.83 | MEN1 (0.83) | KMT2AALDH1A1MEN1POLBHPGD | |
| SCHEMBL3690383 | 0.83 | POLB (0.79) | KMT2AALDH1A1MEN1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628374-B1 | BCL-3 INHIBITORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2023-08-30 | — | — | EP | disclosed |
| EP-3628374-A2 | BCL-3 INHIBITORS | University College Cardiff Consultants Limited (GB) | 2020-04-01 | — | — | EP | disclosed |
| EP-0796233-A1 | RESIN-BOUND PHOSPHONIUM SALTS AND THEIR USE IN ORGANIC SYNTHESIS | SMITHKLINE BEECHAM PLC (GB) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996018592-A1 | RESIN-BOUND PHOSPHONIUM SALTS AND THEIR USE IN ORGANIC SYNTHESIS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-20 | — | — | WO | disclosed |
| US-3987059-A | ALKYL LITHIUM, CYCLIZATION, DEMETALLIZATION | SANDOZ, INC. (US) | 1976-10-19 | — | — | US | disclosed |