Pyrazine

Pyrazine

SCHEMBL8832091

CO.c1cnccn1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrazine SCHEMBL28142624 0.84 TSHR (0.36)
Pyrazine SCHEMBL5179 0.82
Pyrazine SCHEMBL1226089 0.82 TSHR (0.50)
SCHEMBL31437084 0.82 TSHR (0.50)
Pyridine SCHEMBL1206485 0.80
Pyridine SCHEMBL2348132 0.80 NAPRT (0.82)
Pyridine SCHEMBL28910607 0.80 NAPRT (0.82)
Pyridine SCHEMBL15309118 0.80 NAPRT (0.82)
Pyrazine SCHEMBL4235941 0.78
Pyrazine SCHEMBL11731991 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113512219-B Color-adjustable contact lens material and preparation method thereof 东南大学 2022-05-31 CN claimed
CN-111282545-B Two-dimensional van der waals heterojunction and application thereof 东南大学 2022-03-11 CN claimed
CN-113512219-A Color-adjustable contact lens material and preparation method thereof 东南大学 2021-10-19 CN claimed
CN-111282545-A Two-dimensional van der waals heterojunction and application thereof 东南大学 2020-06-16 CN claimed
CN-117680105-A Energy-consumption-free air water production and precipitation bed and preparation method and application thereof 东南大学 2024-03-12 CN disclosed
CN-113351177-B Humidity capturing gel, preparation method and application 东南大学 2022-08-26 CN disclosed
CN-113512219-B Color-adjustable contact lens material and preparation method thereof 东南大学 2022-05-31 CN disclosed
CN-111282545-B Two-dimensional van der waals heterojunction and application thereof 东南大学 2022-03-11 CN disclosed
CN-113512219-A Color-adjustable contact lens material and preparation method thereof 东南大学 2021-10-19 CN disclosed
CN-113351177-A Humidity capturing gel, preparation method and application 东南大学 2021-09-07 CN disclosed
CN-111282545-A Two-dimensional van der waals heterojunction and application thereof 东南大学 2020-06-16 CN disclosed
US-10569231-B2 Fabrication of highly CO2 selective metal-organic framework membrane using liquid phase epitaxy approach KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2020-02-25 US disclosed
US-5532207-A CONTROL OF MONO- AND DI-COTYLEDONOUS ANNUAL, PERENNIAL AND AQUATIC PLANTS; PRE- AND POST-EMERGENCE USE AMERICAN CYANAMID COMPANY (US) 1996-07-02 US disclosed
US-5510319-A PYRROLO-2,3-B-PYRIDINYL DERIVATIVES AMERICAN CYANAMID COMPANY (US) 1996-04-23 US disclosed
US-5364977-A Chemical stabilization and powder processing NIPPON SODA CO., LTD. (JP) 1994-11-15 US disclosed
CN-1026489-C Antirhinoviral (thio) morpholinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA NV (BE) 1994-11-09 CN disclosed
US-5252538-A (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1993-10-12 US disclosed
EP-0227932-B1 NOVEL FUSED PYRIDINE COMPOUNDS, INTERMEDIATES FOR THE PREPARATION OF, AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS AMERICAN CYANAMID COMPANY (US) 1993-01-13 EP disclosed
CN-1047289-A (sulfo-) morpholinyl of rhinovirus and the preparation method of piperazinyl alkylphenol ethers HANSSEN PHARMACEUTICA N V (BE) 1990-11-28 CN disclosed
EP-0227932-A1 Novel fused pyridine compounds, intermediates for the preparation of, and use of said compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1987-07-08 EP disclosed