Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL883611 | 0.82 | LRRK2 (0.72) | LRRK2 | |
| SCHEMBL13834181 | 0.82 | LRRK2 (0.72) | LRRK2 | |
| SCHEMBL3766198 | 0.78 | LRRK2 (0.48) | LRRK2 | |
| SCHEMBL3766207 | 0.78 | LRRK2 (0.48) | LRRK2 | |
| SCHEMBL883605 | 0.75 | LRRK2 (0.48) | LRRK2 | |
| SCHEMBL876184 | 0.74 | LRRK2 (0.62) | LRRK2 | |
| SCHEMBL382602 | 0.72 | LRRK2 (0.65) | LRRK2 | |
| SCHEMBL3770348 | 0.72 | LRRK2 (0.58) | LRRK2 | |
| SCHEMBL3769191 | 0.72 | LRRK2 (0.65) | LRRK2 | |
| SCHEMBL883157 | 0.72 | LRRK2 (0.58) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038743-A1 | PYRAZOLOPYRIDINES AS INHIBITORS OF THE KINASE LRRK2 | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2012-03-29 | — | — | WO | disclosed |