Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 6/20 | 0.56 |
| ▸ | CASP7 | P55210 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16621922 | 0.80 | MEN1 (0.68) | MEN1KMT2ANR1I2AHRCASP1 | |
| SCHEMBL8832020 | 0.78 | MEN1 (0.54) | MEN1KMT2ANR1I2AHRCASP1 | |
| SCHEMBL8831898 | 0.78 | MEN1 (0.54) | MEN1KMT2ANR1I2AHRCASP1 | |
| SCHEMBL15396726 | 0.77 | MAPT (0.45) | MEN1KMT2ANR1I2AHRCASP1 | |
| SCHEMBL8832163 | 0.73 | MEN1 (1.00) | MEN1KMT2ANR1I2AHRCASP1 | |
| SCHEMBL29202644 | 0.73 | KDM4E (0.52) | MEN1KMT2ANR1I2AHRCASP1 | |
| SCHEMBL16945136 | 0.72 | NQO2 (0.55) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL13647624 | 0.72 | NQO2 (0.55) | MEN1KMT2AMAPTMAPK1ALOX15 | |
| SCHEMBL8832275 | 0.72 | MEN1 (0.50) | MEN1KMT2ANR1I2AHRCASP1 | |
| SCHEMBL8349393 | 0.72 | MEN1 (0.70) | MEN1KMT2ANR1I2AHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597921-A | ANTITUMOR AGENTS, TREATMENT OF LEUKEMIA | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0695754-A1 | INDOLO 2,3-b]QUINOXALINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-02-07 | — | — | EP | disclosed |