Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | AHR | P35869 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | CASP1 | P29466 | 2/20 | 0.63 |
| ▸ | CASP7 | P55210 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832020 | 0.89 | MEN1 (0.54) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8832521 | 0.87 | MEN1 (0.55) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8831953 | 0.87 | MEN1 (0.55) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8832163 | 0.79 | MEN1 (1.00) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8349393 | 0.78 | MEN1 (0.70) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL16621922 | 0.76 | MEN1 (0.68) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8348445 | 0.75 | KMT2A (0.67) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL11180483 | 0.74 | MEN1 (0.68) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL2713434 | 0.74 | CYP2A6 (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL31711447 | 0.74 | CYP2A6 (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597921-A | ANTITUMOR AGENTS, TREATMENT OF LEUKEMIA | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0695754-A1 | INDOLO 2,3-b]QUINOXALINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-02-07 | — | — | EP | disclosed |