Ethylbenzene

Ethylbenzene

SCHEMBL8832672

CCc1ccccc1.C[SiH](Cl)Cl

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.74
ALDH1A1 P00352 2/20 0.44
CALM1 P0DP23 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
RAB9A P51151 2/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 3/20 0.39
MAPK1 P28482 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
IDO1 P14902 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL27961581 0.95 TP53 (0.74) TP53ALDH1A1CALM1CYP1A2CYP2A6
Ethylbenzene SCHEMBL306950 0.92 TP53 (0.78) TP53ALDH1A1CALM1CYP1A2CYP2A6
Ethylbenzene SCHEMBL11352852 0.87 TP53 (0.70) TP53ALDH1A1CALM1CYP1A2CYP2A6
Ethylbenzene SCHEMBL3987542 0.86 TP53 (1.00) TP53ALDH1A1CALM1CYP1A2CYP2A6
Ethylbenzene SCHEMBL7458207 0.86 TP53 (1.00) TP53ALDH1A1CALM1CYP1A2CYP2A6
Ethylbenzene SCHEMBL11223212 0.86 TP53 (1.00) TP53ALDH1A1CALM1CYP1A2CYP2A6
Ethylbenzene SCHEMBL1330604 0.86
Ethylbenzene SCHEMBL1332452 0.86
Ethylbenzene SCHEMBL1331299 0.86
Ethylbenzene SCHEMBL27395806 0.86 TP53 (1.00) TP53ALDH1A1CALM1CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5622784-A WATERPROOFING; MODIFIED SILICON DIOXIDE THIN FILM SEIKO EPSON CORPORATION (JP) 1997-04-22 US disclosed