Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835115 | 0.92 | HTR2C (0.48) | HTR2CHTR2B | |
| SCHEMBL8835083 | 0.86 | — | — | |
| SCHEMBL8540727 | 0.83 | HTR2C (0.40) | HTR2CHTR2B | |
| SCHEMBL8835041 | 0.82 | — | — | |
| SCHEMBL8835187 | 0.78 | — | — | |
| SCHEMBL8835190 | 0.78 | — | — | |
| SCHEMBL8835345 | 0.78 | PDGFRA (0.40) | — | |
| SCHEMBL9161107 | 0.77 | — | — | |
| SCHEMBL8835100 | 0.76 | — | — | |
| SCHEMBL8835075 | 0.76 | MALT1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5596001-A | 4-aryl-3-(heteroarylureido)quinoline derivatves | PFIZER INC. (US) | 1997-01-21 | — | — | US | claimed |
| EP-0590094-A1 | 4-ARYL-3-(HETEROARYLUREIDO)QUINOLINE DERIVATIVES | PFIZER INC. (US) | 1994-04-06 | — | — | EP | claimed |
| WO-1992019614-A1 | 4-ARYL-3-(HETEROARYLUREIDO)QUINOLINE DERIVATIVES | PFIZER INC. (US) | 1992-11-12 | — | — | WO | claimed |
| US-5596001-A | 4-aryl-3-(heteroarylureido)quinoline derivatves | PFIZER INC. (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0590094-A1 | 4-ARYL-3-(HETEROARYLUREIDO)QUINOLINE DERIVATIVES | PFIZER INC. (US) | 1994-04-06 | — | — | EP | disclosed |
| WO-1992019614-A1 | 4-ARYL-3-(HETEROARYLUREIDO)QUINOLINE DERIVATIVES | PFIZER INC. (US) | 1992-11-12 | — | — | WO | disclosed |