SCHEMBL8835102

SCHEMBL8835102

CCC=CC=CC1CCC(c2ccc(CCCC)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 13/20 0.51
SPHK2 Q9NRA0 7/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8835098 1.00 SPHK1 (0.51) SPHK1SPHK2
SCHEMBL8835056 0.92 SPHK1 (0.43) SPHK1SPHK2
SCHEMBL8835061 0.92 SPHK1 (0.43) SPHK1SPHK2
SCHEMBL8835352 0.86 SPHK1 (0.36) SPHK1SPHK2
SCHEMBL8835355 0.86 SPHK1 (0.36) SPHK1SPHK2
SCHEMBL8835444 0.84 SPHK1 (0.58) SPHK1SPHK2
SCHEMBL8835446 0.84 SPHK1 (0.58) SPHK1SPHK2
SCHEMBL8453613 0.83 SPHK1 (0.48) SPHK1SPHK2
SCHEMBL8453623 0.83 SPHK1 (0.48) SPHK1SPHK2
SCHEMBL8453618 0.83 SPHK1 (0.48) SPHK1SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5662830-A Diene derivative CHISSO CORPORATION (JP) 1997-09-02 US disclosed
US-5609791-A Diene derivative CHISSO CORPORATION (JP) 1997-03-11 US disclosed
EP-0563982-B1 Polycyclic diene derivatives CHISSO CORP (JP) 1996-07-17 EP disclosed
US-5449810-A Diene derivative CHISSO CORPORATION (JP) 1995-09-12 US disclosed
EP-0563982-A2 Polycyclic diene derivatives Chisso Corporation (JP) 1993-10-06 EP disclosed