SCHEMBL8835103

SCHEMBL8835103

[CH2]CCC(c1ccc(C(C)C)cc1)c1ccc(C(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.39
USP5 P45974 1/20 0.38
TYR P14679 2/20 0.38
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP3A4 P08684 2/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
HIF1A Q16665 1/20 0.36
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36
SMPD1 P17405 1/20 0.36
DRD1 P21728 1/20 0.36
TBXA2R P21731 1/20 0.36
ADRA1A P35348 1/20 0.36
OPRM1 P35372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5013820 0.81 CYP19A1 (0.44) SLC6A3HTR1ACASRCYP2C19HRH1
SCHEMBL270397 0.77 HRH1 (0.56) CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL28547563 0.76 HRH1 (0.34) SLC6A4HRH1HTR2A
SCHEMBL757076 0.76 CYP19A1 (0.44) IDO1LMNAHTTMAPK1MEN1
SCHEMBL536973 0.76 CNR1 (0.43) TYRCYP2D6CYP2C9CYP3A4SLC6A2
SCHEMBL10654305 0.76 CYP19A1 (0.49) CYP2D6CASRLMNACYP1A2CYP2C19
SCHEMBL8753491 0.75 HRH1 (0.54) CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3
Hydrogen Peroxide SCHEMBL461155 0.73 TYR (0.55) IDO1USP5TYRCYP2D6CYP2C9
Hydrogen Peroxide SCHEMBL20915049 0.73 TYR (0.55) IDO1USP5TYRCYP2D6CYP2C9
Benzene SCHEMBL5833599 0.73 TYR (0.52) IDO1USP5TYRCYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5608099-A Process for the recovery of tributyl phosphate from spent hydraulic oils BAYER AKTIENGESELLSCHAFT (DE) 1997-03-04 US disclosed