Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835275 | 1.00 | HTR2C (0.46) | HTR2CDRD2DRD4GRM2HDAC2 | |
| SCHEMBL8835710 | 0.97 | HTR2C (0.49) | HTR2CDRD2DRD4GRM2HDAC2 | |
| SCHEMBL8835704 | 0.97 | HTR2C (0.49) | HTR2CDRD2DRD4GRM2HDAC2 | |
| SCHEMBL13433665 | 0.91 | HTR2C (0.49) | HTR2CDRD2DRD4GRM2HDAC2 | |
| SCHEMBL8835522 | 0.86 | HTR2C (0.46) | HTR2CDRD2DRD4GRM2HDAC2 | |
| SCHEMBL8835518 | 0.86 | HTR2C (0.46) | HTR2CDRD2DRD4GRM2HDAC2 | |
| SCHEMBL8835414 | 0.85 | HTR2C (0.43) | HTR2CHDAC2CNR1KDM4EALDH1A1 | |
| SCHEMBL8455174 | 0.84 | HTR2C (0.42) | HTR2CHDAC2CNR1MAOBKDM4E | |
| SCHEMBL8455164 | 0.84 | HTR2C (0.42) | HTR2CHDAC2CNR1MAOBKDM4E | |
| SCHEMBL8455168 | 0.84 | HTR2C (0.42) | HTR2CHDAC2CNR1MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0563982-A2 | Polycyclic diene derivatives | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |