Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228247 | 1.00 | SPHK1 (0.43) | SPHK1SPHK2CYP2C9HDAC2 | |
| SCHEMBL8835311 | 1.00 | SPHK1 (0.43) | SPHK1SPHK2CYP2C9HDAC2 | |
| SCHEMBL8835314 | 0.97 | SPHK1 (0.44) | SPHK1SPHK2CYP2C9HDAC2 | |
| SCHEMBL8835313 | 0.97 | SPHK1 (0.44) | SPHK1SPHK2CYP2C9HDAC2 | |
| SCHEMBL8835353 | 0.91 | SPHK1 (0.56) | SPHK1SPHK2 | |
| SCHEMBL8835356 | 0.91 | SPHK1 (0.56) | SPHK1SPHK2 | |
| SCHEMBL8835278 | 0.89 | SPHK1 (0.35) | SPHK1SPHK2CYP2C9HDAC2 | |
| SCHEMBL8835277 | 0.89 | SPHK1 (0.35) | SPHK1SPHK2CYP2C9HDAC2 | |
| SCHEMBL8835245 | 0.88 | SPHK1 (0.42) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL8835444 | 0.88 | SPHK1 (0.58) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |