Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 9/20 | 0.48 |
| ▸ | CA9 | Q16790 | 7/20 | 0.48 |
| ▸ | GLA | P06280 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA6 | P23280 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | CA5A | P35218 | 3/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834944 | 0.84 | IGLV6-57 (0.58) | KDM4EALDH1A1HPGDHTTGLA | |
| SCHEMBL8834872 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HPGDHTTCA12 | |
| SCHEMBL7915718 | 0.81 | CA12 (0.52) | KDM4EALDH1A1HPGDHTTCA12 | |
| SCHEMBL14802512 | 0.76 | CA12 (0.59) | KDM4EALDH1A1HPGDHTTCA12 | |
| SCHEMBL14473801 | 0.76 | CA12 (0.63) | KDM4EALDH1A1HPGDHTTCA12 | |
| SCHEMBL14329509 | 0.76 | CA12 (0.63) | KDM4EALDH1A1HPGDHTTCA12 | |
| SCHEMBL8368509 | 0.75 | CA12 (0.68) | KDM4EALDH1A1HPGDCA12CA9 | |
| SCHEMBL14329526 | 0.74 | CA12 (0.61) | KDM4EALDH1A1HPGDHTTCA12 | |
| SCHEMBL14802612 | 0.74 | CA12 (0.56) | KDM4EALDH1A1HPGDHTTCA12 | |
| 7-Isopropoxycoumarin SCHEMBL14329508 | 0.73 | KDM4E (0.69) | KDM4EALDH1A1HPGDHTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | disclosed |