Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835433 | 0.96 | SPHK1 (0.50) | SPHK1SPHK2CYP2C9S1PR2S1PR4 | |
| SCHEMBL8835561 | 0.96 | SPHK1 (0.50) | SPHK1SPHK2CYP2C9S1PR2S1PR4 | |
| SCHEMBL8835266 | 0.91 | CYP2C9 (0.43) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL8835370 | 0.88 | CYP2C9 (0.40) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL8835059 | 0.88 | CYP2C9 (0.40) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL8835097 | 0.88 | SPHK1 (0.56) | SPHK1SPHK2THRATHRB | |
| SCHEMBL8835317 | 0.86 | CYP2C9 (0.42) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL9477590 | 0.85 | SPHK1 (0.56) | SPHK1SPHK2CYP2C9S1PR2S1PR4 | |
| SCHEMBL9477599 | 0.85 | SPHK1 (0.56) | SPHK1SPHK2CYP2C9S1PR2S1PR4 | |
| SCHEMBL9477593 | 0.85 | SPHK1 (0.56) | SPHK1SPHK2CYP2C9S1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0563982-A2 | Polycyclic diene derivatives | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |