Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 2/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835585 | 1.00 | CYP1A2 (0.36) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL8835249 | 0.88 | TLR4 (0.32) | CYP2C9 | |
| SCHEMBL8835243 | 0.88 | TLR4 (0.32) | CYP2C9 | |
| SCHEMBL9481648 | 0.83 | CYP1A2 (0.41) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL2271711 | 0.83 | CYP1A2 (0.41) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL7556351 | 0.83 | CYP1A2 (0.41) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL7902013 | 0.83 | CYP1A2 (0.41) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL7902022 | 0.83 | CYP1A2 (0.41) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL2271708 | 0.83 | CYP1A2 (0.41) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL7557945 | 0.83 | CYP1A2 (0.41) | CYP1A2PKMHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |