SCHEMBL8835643

SCHEMBL8835643

COc1ccc(OC(=O)c2ccc(O)cc2O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.64
CA12 O43570 3/20 0.64
CA1 P00915 3/20 0.64
CA2 P00918 3/20 0.64
CA7 P43166 3/20 0.64
CA9 Q16790 3/20 0.64
CA14 Q9ULX7 3/20 0.64
PDK4 Q16654 2/20 0.64
CYP3A4 P08684 6/20 0.61
HPGD P15428 5/20 0.61
ALDH1A1 P00352 4/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
ATM Q13315 1/20 0.61
MAPT P10636 3/20 0.60
PPARG P37231 1/20 0.60
HSP90AA1 P07900 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9010718 0.90 CA12 (0.61) PDK2CA12CA1CA2CA7
SCHEMBL10608463 0.87 CA12 (0.59) PDK2CA12CA1CA2CA7
SCHEMBL1484204 0.85 HPGD (0.65) CYP3A4HPGDALDH1A1MEN1KMT2A
SCHEMBL18121565 0.84 ESR1 (0.52) PDK2PDK4CYP3A4HPGDALDH1A1
SCHEMBL10611188 0.83 MAPT (0.61) PDK2CA12CA1CA2CA7
SCHEMBL4201347 0.83 MAPT (0.71) PDK2CA12CA1CA2CA7
SCHEMBL12634385 0.83 APP (0.64) PDK2CA12CA1CA2CA7
SCHEMBL12634391 0.81 HPGD (0.60) CYP3A4HPGDALDH1A1KMT2ANPC1
SCHEMBL10893093 0.81 CYP3A4 (0.68) PDK2CA12CA1CA2CA7
SCHEMBL2281149 0.81 CA12 (0.69) PDK2CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9315005-A None JP disclosed
JP-H09315005-A THERMAL RECORDING BODY OJI PAPER CO LTD 1997-12-09 JP disclosed