Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 5/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835669 | 1.00 | KDM1A (0.44) | KDM1ACHRM2DRD2CHRNB2DRD4 | |
| SCHEMBL8835660 | 1.00 | KDM1A (0.44) | KDM1ACHRM2DRD2CHRNB2DRD4 | |
| SCHEMBL8835216 | 0.96 | KDM1A (0.42) | KDM1ACHRM2DRD2CHRNB2DRD4 | |
| SCHEMBL8835219 | 0.96 | KDM1A (0.42) | KDM1ACHRM2DRD2CHRNB2DRD4 | |
| SCHEMBL8835224 | 0.96 | KDM1A (0.42) | KDM1ACHRM2DRD2CHRNB2DRD4 | |
| SCHEMBL13002283 | 0.87 | KDM1A (0.50) | KDM1ACHRM2DRD2CHRNB2DRD4 | |
| SCHEMBL8834861 | 0.85 | KDM1A (0.43) | KDM1ACHRM2DRD2CHRNB2DRD4 | |
| SCHEMBL8834859 | 0.85 | KDM1A (0.43) | KDM1ACHRM2DRD2CHRNB2DRD4 | |
| SCHEMBL8836053 | 0.84 | HTR2A (0.33) | KDM1AHTR2AKCNH2 | |
| SCHEMBL8836059 | 0.84 | HTR2A (0.33) | KDM1AHTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |