Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8479186 | 0.99 | TACR1 (0.48) | TACR1 | |
| SCHEMBL9240525 | 0.88 | TACR1 (0.50) | TACR1 | |
| SCHEMBL8479847 | 0.88 | TACR1 (0.50) | TACR1 | |
| Hydrochloric Acid SCHEMBL9237240 | 0.87 | TACR1 (0.49) | TACR1 | |
| Hydrochloric Acid SCHEMBL8476619 | 0.87 | TACR1 (0.49) | TACR1 | |
| SCHEMBL6133084 | 0.87 | TACR1 (0.54) | TACR1 | |
| SCHEMBL8476041 | 0.87 | TACR1 (0.48) | TACR1 | |
| SCHEMBL9237571 | 0.86 | TACR1 (0.47) | TACR1 | |
| SCHEMBL8481444 | 0.86 | TACR1 (0.47) | TACR1 | |
| Hydrochloric Acid SCHEMBL8481316 | 0.86 | TACR1 (0.53) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670505-A | TACHYKIKIN ANTAGONIST FOR RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0655442-A1 | Piperazine derivatives as Tachykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-31 | — | — | EP | disclosed |