SCHEMBL8836685

SCHEMBL8836685

CN(C)NC(=O)CN1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(Cc2c[nH]c3ccccc23)C1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9238985 1.00 TACR1 (0.72) TACR1
Hydrochloric Acid SCHEMBL8836208 0.91 TACR1 (0.74) TACR1
Hydrochloric Acid SCHEMBL7825649 0.91 TACR1 (0.74) TACR1
Hydrochloric Acid SCHEMBL8475494 0.90 TACR1 (0.75) TACR1
Hydrochloric Acid SCHEMBL7823925 0.90 TACR1 (0.75) TACR1
SCHEMBL9240877 0.90 TACR1 (0.73) TACR1
SCHEMBL7827721 0.89 TACR1 (0.73) TACR1
SCHEMBL8481354 0.89 TACR1 (0.73) TACR1
SCHEMBL7826987 0.89 TACR1 (0.72) TACR1
SCHEMBL8836473 0.89 TACR1 (0.72) TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5670505-A TACHYKIKIN ANTAGONIST FOR RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND ANTIINFLAMMATORY AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-09-23 US disclosed