Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26604899 | 0.86 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL27544439 | 0.86 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL27189538 | 0.85 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL5732900 | 0.85 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL5734037 | 0.85 | CYP4F2 (0.55) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL30954335 | 0.85 | CYP4F2 (0.55) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL5734529 | 0.85 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL30832846 | 0.84 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL1663438 | 0.84 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL5734032 | 0.84 | CYP1A2 (0.56) | MEN1KMT2ANPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616809-A | COUPLER, USED TO DYE KERATINOUS FIBERS | L'OREAL (FR) | 1997-04-01 | — | — | US | disclosed |
| EP-0591060-B1 | 4-Substituted meta amino phenols, process for their preparation their use in dyeing keratinic fibres and intermediates used in their preparation | OREAL (FR) | 1996-12-18 | — | — | EP | disclosed |
| US-5451236-A | Hair dyes | L'OREAL (FR) | 1995-09-19 | — | — | US | disclosed |
| EP-0591060-A1 | 4-Substituted meta amino phenols, process for their preparation their use in dyeing keratinic fibres and intermediates used in their preparation | L'OREAL (FR) | 1994-04-06 | — | — | EP | disclosed |