Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718255 | 0.81 | MAPT (0.74) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL1028694 | 0.77 | MAPT (0.62) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL126110 | 0.75 | MAPT (0.61) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL9471773 | 0.74 | MAPT (0.65) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL9471765 | 0.74 | MAPT (0.65) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL880161 | 0.74 | SRC (0.60) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL789918 | 0.73 | MAPT (0.62) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL4126863 | 0.73 | MAPT (0.62) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL20505550 | 0.73 | MAPT (0.68) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL123842 | 0.73 | MAPT (0.62) | MAPTMEN1KMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616809-A | COUPLER, USED TO DYE KERATINOUS FIBERS | L'OREAL (FR) | 1997-04-01 | — | — | US | disclosed |
| EP-0591060-B1 | 4-Substituted meta amino phenols, process for their preparation their use in dyeing keratinic fibres and intermediates used in their preparation | OREAL (FR) | 1996-12-18 | — | — | EP | disclosed |
| US-5451236-A | Hair dyes | L'OREAL (FR) | 1995-09-19 | — | — | US | disclosed |
| EP-0591060-A1 | 4-Substituted meta amino phenols, process for their preparation their use in dyeing keratinic fibres and intermediates used in their preparation | L'OREAL (FR) | 1994-04-06 | — | — | EP | disclosed |
| US-4171361-A | HYPOTENSIVE | ELI LILLY AND COMPANY (US) | 1979-10-16 | — | — | US | disclosed |