Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664875 | 1.00 | HTR2C (0.39) | HTR2CHTR2BTAAR1CYP2D6SLC6A2 | |
| SCHEMBL8664873 | 1.00 | HTR2C (0.39) | HTR2CHTR2BTAAR1CYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL8662877 | 0.98 | HTR2C (0.41) | HTR2CHTR2BTAAR1CYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL8837315 | 0.98 | HTR2C (0.41) | HTR2CHTR2BTAAR1CYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL8662881 | 0.98 | HTR2C (0.41) | HTR2CHTR2BTAAR1CYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL8837316 | 0.86 | MEN1 (0.41) | HTR2CHTR2BTAAR1CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL8661008 | 0.86 | MEN1 (0.41) | HTR2CHTR2BTAAR1CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL8661010 | 0.86 | MEN1 (0.41) | HTR2CHTR2BTAAR1CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL8837347 | 0.79 | HTR2C (0.40) | HTR2CHTR2BGRM5 | |
| Hydrochloric Acid SCHEMBL8662444 | 0.79 | HTR2C (0.40) | HTR2CHTR2BGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648347-A | ANTIDEPRESSANTS | GLAXO WELLCOME INC. (US) | 1997-07-15 | — | — | US | disclosed |