Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL7629511 | 0.95 | FFAR3 (0.72) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL3090254 | 0.92 | FFAR3 (0.77) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL315107 | 0.92 | FFAR3 (0.77) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL487253 | 0.89 | — | — | |
| Butyric Acid SCHEMBL7947676 | 0.89 | FFAR3 (0.81) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL7952938 | 0.89 | FFAR3 (0.81) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL1545708 | 0.88 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL4884624 | 0.87 | FFAR3 (0.68) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL5655493 | 0.87 | FFAR3 (0.68) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL5415080 | 0.86 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674714-A | CULTURE PRODUCT FROM STREPTOMYCES GROWN IN CULTURE CONTAINING SOYBEAN FLOUR, GENESTEIN OR GENISTIN AS PROMOTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| EP-0419567-B1 | PROCESS FOR INDUCING CYTOCHROME P-450 ENZYMES IN STREPTOMYCES-BACTERIA AND DETERMINING THE MUTAGENICITY OF CHEMICALS | DU PONT (US) | 1994-03-23 | — | — | EP | disclosed |
| EP-0273771-B1 | MUTAGENIC EVALUATION METHOD | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5213971-A | Process for inducing cytochrome P-450 enzymes in Streptomyces bacteria and determining the mutagenicity of chemicals | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-25 | — | — | US | disclosed |
| US-5169755-A | Culturing on a soybean derivative; incubating an amino acid requiring mutant strain of Salmonella in presence of culture; relating ratio of amino acid sufficient revertant colonies to control | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0347226-A1 | Process for inducing cytochrome p-450 enzymes in streptomyces bacteria and determining the mutagenicity of chemicals | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-12-20 | — | — | EP | disclosed |
| EP-0273771-A2 | Mutagenic evaluation method | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |