SCHEMBL8837641

SCHEMBL8837641

O=C(Oc1cccc2cc3cccc(OC(=O)c4ccc(O)cc4)c3cc12)c1ccc(O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.50
ESR1 P03372 6/20 0.50
ESR2 Q92731 6/20 0.50
MEN1 O00255 3/20 0.50
HSD17B10 Q99714 3/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
JAK2 O60674 1/20 0.50
USP2 O75604 1/20 0.50
ALOX15 P16050 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ALOX5 P09917 2/20 0.46
PTGES O14684 1/20 0.46
SLC2A1 P11166 1/20 0.46
SLC2A4 P14672 1/20 0.46
POLB P06746 2/20 0.44
SERPINE1 P05121 1/20 0.44
LMNA P02545 1/20 0.43
METAP2 P50579 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8756174 0.95 ESR1 (0.51) KMT2AESR1ESR2MEN1HSD17B10
SCHEMBL8756256 0.89 ESR1 (0.51) KMT2AESR1ESR2MEN1HSD17B10
SCHEMBL767398 0.89 ESR1 (0.49) KMT2AESR1ESR2MEN1HSD17B10
SCHEMBL7541679 0.85 KMT2A (0.59) KMT2AESR1ESR2MEN1HSD17B10
SCHEMBL777893 0.84 ESR1 (0.67) KMT2AESR1ESR2MEN1HSD17B10
SCHEMBL11592836 0.84 KMT2A (0.48) KMT2AESR1ESR2MEN1HSD17B10
SCHEMBL8837626 0.82 ESR1 (0.50) KMT2AESR1ESR2MEN1HSD17B10
SCHEMBL27977417 0.82 KMT2A (0.59) KMT2AESR1ESR2MEN1HSD17B10
SCHEMBL8756192 0.82 SLC2A1 (0.61) KMT2AESR1ESR2MEN1HSD17B10
SCHEMBL8755465 0.81 SLC2A1 (0.50) KMT2AESR1ESR2MEN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677112-A USING AN ANTHRACENE COMPOUND WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-14 US disclosed
US-5576359-A ANTHRACENE DERIVATIVE, SOLVENT, COMPOUND CONTAINING GLYCIDYL GROUPS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1996-11-19 US disclosed
EP-0636941-B1 Deep ultraviolet absorbent and its use in pattern formation WAKO PURE CHEM IND LTD (JP) 1996-03-20 EP disclosed
EP-0636941-A1 Deep ultraviolet absorbent and its use in pattern formation WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1995-02-01 EP disclosed