Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.43 |
| ▸ | CNR1 | P21554 | 10/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837829 | 0.90 | CNR2 (0.39) | CNR2CNR1SMN1; SMN2ALDH1A1CREBBP | |
| SCHEMBL8837853 | 0.82 | SMN1; SMN2 (0.60) | CNR2CNR1SMN1; SMN2ALDH1A1CREBBP | |
| SCHEMBL9236163 | 0.78 | CNR2 (0.45) | CNR2CNR1SMN1; SMN2CREBBP | |
| SCHEMBL28774046 | 0.77 | CNR2 (0.47) | CNR2CNR1CREBBPKMT2A | |
| SCHEMBL9238742 | 0.77 | SMN1; SMN2 (0.55) | CNR2CNR1SMN1; SMN2ALDH1A1CREBBP | |
| SCHEMBL2538347 | 0.75 | ABCG2 (0.57) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2538344 | 0.75 | ABCG2 (0.57) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8837827 | 0.74 | CREBBP (0.63) | CNR2SMN1; SMN2ALDH1A1CREBBPKMT2A | |
| SCHEMBL7007076 | 0.73 | CNR2 (0.41) | CNR2CNR1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL17943528 | 0.72 | CNR2 (0.48) | CNR2CNR1SMN1; SMN2ALDH1A1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | disclosed |