Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.81 |
| ▸ | ABL1 | P00519 | 4/20 | 0.69 |
| ▸ | BCR | P11274 | 4/20 | 0.69 |
| ▸ | PRKCA | P17252 | 4/20 | 0.69 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | PRKACA | P17612 | 2/20 | 0.56 |
| ▸ | PRKACG | P22612 | 2/20 | 0.56 |
| ▸ | PRKACB | P22694 | 2/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 4/20 | 0.52 |
| ▸ | CDK1 | P06493 | 3/20 | 0.52 |
| ▸ | MTOR | P42345 | 3/20 | 0.52 |
| ▸ | SMG1 | Q96Q15 | 3/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.52 |
| ▸ | CDK4 | P11802 | 2/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.52 |
| ▸ | CCND1 | P24385 | 2/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837798 | 0.91 | CSNK2A1 (0.81) | CSNK2A1ABL1BCRPRKCAEGFR | |
| SCHEMBL8837873 | 0.91 | CSNK2A1 (0.90) | CSNK2A1ABL1BCRPRKCAEGFR | |
| SCHEMBL8837831 | 0.90 | CSNK2A1 (0.81) | CSNK2A1ABL1BCRPRKCAEGFR | |
| SCHEMBL8837780 | 0.89 | CSNK2A1 (1.00) | CSNK2A1ABL1BCRPRKCAEGFR | |
| SCHEMBL8837770 | 0.89 | CSNK2A1 (0.83) | CSNK2A1ABL1BCRPRKCAEGFR | |
| SCHEMBL8837799 | 0.89 | CSNK2A1 (0.82) | CSNK2A1ABL1BCRPRKCAEGFR | |
| SCHEMBL8837826 | 0.88 | CSNK2A1 (0.76) | CSNK2A1ABL1BCRPRKCAEGFR | |
| SCHEMBL8837797 | 0.88 | CSNK2A1 (0.79) | CSNK2A1ABL1BCRPRKCAEGFR | |
| Monoethanolamine SCHEMBL8837869 | 0.88 | CSNK2A1 (0.84) | CSNK2A1ABL1BCRPRKCAEGFR | |
| SCHEMBL8837871 | 0.88 | CSNK2A1 (0.73) | CSNK2A1ABL1BCRPRKCAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | claimed |
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | disclosed |