⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362264 | 0.65 | — | — | |
| SCHEMBL11973662 | 0.60 | — | — | |
| SCHEMBL1553497 | 0.59 | — | — | |
| SCHEMBL2273694 | 0.59 | — | — | |
| SCHEMBL12160740 | 0.57 | — | — | |
| SCHEMBL357257 | 0.57 | — | — | |
| SCHEMBL13721426 | 0.57 | — | — | |
| SCHEMBL122515 | 0.57 | — | — | |
| SCHEMBL20614486 | 0.55 | CREBBP (0.52) | — | |
| SCHEMBL1372797 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553096-B1 | PYRAZOLE COMPOUNDS | UBE INDUSTRIES (JP) | 2012-10-31 | — | — | EP | claimed |
| EP-1459742-B9 | Agent for prophylaxis and treatment of asthenopia and pseudomyopia | SENJU PHARMA CO (JP) | 2012-05-02 | — | — | EP | claimed |
| EP-1459742-B1 | Agent for prophylaxis and treatment of asthenopia and pseudomyopia | SENJU PHARMA CO (JP) | 2011-10-12 | — | — | EP | claimed |
| EP-1295607-B9 | ANTITUMOR EFFECT POTENTIATORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-10-05 | — | — | EP | claimed |
| US-7956072-B2 | Agent for repairing corneal sensitivity containing amide compound | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2011-06-07 | — | — | US | claimed |
| EP-1177796-B1 | Medicament for prevention or therapeutic treatment of liver disease | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-04-27 | — | — | EP | claimed |
| EP-0956865-B2 | MEDICINES COMPRISING Rho KINASE INHIBITOR | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-08-18 | — | — | EP | claimed |
| EP-2200440-A1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | Crestone, Inc. (US) | 2010-06-30 | — | — | EP | claimed |
| EP-1295607-B1 | ANTITUMOR EFFECT POTENTIATORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-04-28 | — | — | EP | claimed |
| US-20090247552-A1 | AQUEOUS LIQUID PREPARATION CONTAINING AMIDE COMPOUND | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2009-10-01 | — | — | US | claimed |
| EP-1163910-A1 | PREVENTIVES/REMEDIES FOR INTERSTITIAL PNEUMONIA AND PULMONARY FIBROSIS | Welfide Corporation (JP) | 2001-12-19 | — | — | EP | claimed |
| EP-1034793-A1 | PREVENTIVES/REMEDIES FOR GLAUCOMA | Senju Pharmaceutical Co., Ltd. (JP) | 2000-09-13 | — | — | EP | claimed |
| EP-0956865-A1 | MEDICINES COMPRISING Rho KINASE INHIBITOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-11-17 | — | — | EP | claimed |
| WO-1999031071-A1 | NEW PHTHALAZINONES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-06-24 | — | — | WO | claimed |
| EP-0280224-B1 | Substituted 3H-indoles, process for their preparation and medicines containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-06-01 | — | — | EP | claimed |
| EP-0223937-B1 | INDOLES SUBSTITUTED WITH HETEROCYCLES, INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1992-03-18 | — | — | EP | claimed |
| US-4925845-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-05-15 | — | — | US | claimed |
| US-4851406-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-25 | — | — | US | claimed |
| EP-0240026-A1 | Heterocyclically substituted benzimidazoles, method for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1987-10-07 | — | — | EP | claimed |
| EP-0223937-A1 | Indoles substituted with heterocycles, intermediates, process for their preparation and medicaments | Roche Diagnostics GmbH (DE) | 1987-06-03 | — | — | EP | claimed |