Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.45 |
| ▸ | NPY2R | P49146 | 5/20 | 0.43 |
| ▸ | NPY4R | P50391 | 5/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.43 |
| ▸ | NPY1R | P25929 | 4/20 | 0.43 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8838927 | 1.00 | CALCRL (0.46) | CALCRLCTSDBACE1NPY2RNPY4R | |
| SCHEMBL29844485 | 0.91 | CALCRL (0.48) | CALCRLCTSDBACE1NPY2RNPY4R | |
| SCHEMBL30974359 | 0.88 | BACE1 (0.53) | CALCRLCTSDBACE1NPY2RNPY4R | |
| SCHEMBL30658587 | 0.87 | F2 (0.46) | CTSDBACE1NPY2RNPY4RNPY5R | |
| SCHEMBL30123066 | 0.86 | NTSR2 (0.48) | CALCRLCTSDBACE1NTSR2NTSR1 | |
| SCHEMBL30495649 | 0.85 | NPY2R (0.50) | CALCRLNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30844349 | 0.85 | CALCRL (0.47) | CALCRLCTSDBACE1NTSR2NTSR1 | |
| SCHEMBL30844323 | 0.84 | CALCRL (0.49) | CALCRLCTSDBACE1NPY2RNPY4R | |
| SCHEMBL30844326 | 0.84 | F2 (0.48) | CALCRLCTSDBACE1NPY2RNPY4R | |
| SCHEMBL9436235 | 0.84 | CALCRL (0.45) | CALCRLNTSR2NTSR1SORT1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35491-E | DIAGNOSTIC SCREENING MALIGNANCY BY A PROBE POLYNUCLEOTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-04-08 | — | — | US | claimed |
| US-4699877-A | Methods and compositions for detecting human tumors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1987-10-13 | — | — | US | disclosed |