Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651160 | 0.84 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL31621131 | 0.84 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL3190479 | 0.84 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL6142430 | 0.84 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL9488008 | 0.84 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL28877228 | 0.84 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL420649 | 0.82 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4LMNA | |
| SCHEMBL423893 | 0.82 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4LMNA | |
| SCHEMBL10401487 | 0.81 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL28368297 | 0.81 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790884-A1 | METHOD OF APERTURING THIN SHEET MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014191-A1 | METHOD OF APERTURING THIN SHEET MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-17 | — | — | WO | disclosed |