SCHEMBL8840316

SCHEMBL8840316

CC(=CCCCCc1ccc2ccc3cccc4ccc1c2c34)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.60
MEN1 O00255 1/20 0.60
TBXAS1 P24557 1/20 0.44
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 4/20 0.40
HPGD P15428 3/20 0.40
MAPT P10636 2/20 0.40
HSD17B10 Q99714 3/20 0.38
POLB P06746 2/20 0.38
CYP1A2 P05177 1/20 0.38
GLA P06280 1/20 0.38
CYP2D6 P10635 1/20 0.38
FAAH O00519 1/20 0.37
MTNR1A P48039 2/20 0.36
HTT P42858 1/20 0.35
ITPR1 Q14643 1/20 0.35
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1497446 0.82 KMT2A (0.52) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL5416773 0.78 KMT2A (0.42) KMT2AMEN1TBXAS1KDM4EALDH1A1
SCHEMBL18196118 0.78 KMT2A (0.49) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL9911142 0.78 KMT2A (0.74) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL31484738 0.77 KMT2A (0.77) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL9911140 0.77 KMT2A (0.68) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL9911141 0.77 KMT2A (0.68) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL10906640 0.76 KMT2A (0.94) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL15536514 0.76 KMT2A (0.59) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL10789805 0.76 KMT2A (0.59) KMT2AMEN1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5672760-A OBTAINING A PHOTOABSORBER-CONTAINING ACRYLIC POLYMER BY USING N-2-HYDROXYETHYL-N-ETHYL ANILINE TO OBTAIN 4-((2-HYDROXYETHYL)ETHYLAMINO)-4'-(TRIFLUOROMETHYLSULFONYL)-TOLANE WHICH REACTS WITH A POLYMERIZABLE METHACRYLIC ACID INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-09-30 US disclosed