Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TPMT | P51580 | 4/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644194 | 0.88 | TTR (0.62) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL8840252 | 0.84 | TTR (0.54) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL8840346 | 0.82 | TTR (0.52) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL8840267 | 0.81 | TTR (0.50) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL25977593 | 0.76 | TTR (0.59) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL11679297 | 0.76 | TTR (0.54) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL31701026 | 0.74 | TTR (0.52) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL31174965 | 0.74 | TTR (0.52) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL31049112 | 0.74 | TTR (0.52) | TTRTSHRTPMTSRD5A2PLAU | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL11350560 | 0.74 | TPMT (0.45) | TTRTSHRTPMTHCAR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6340605-A | — | — | None | — | — | JP | disclosed |
| US-5607977-A | PESTICIDES | SHELL AGRAR GMBH & CO. KG (DE) | 1997-03-04 | — | — | US | disclosed |
| JP-H06340605-A | INTERMEDIATE AND ITS PREPARATION | SHELL INTERNATL RES MAATSCHAPPIJ BV | 1994-12-13 | — | — | JP | disclosed |