SCHEMBL8840397

SCHEMBL8840397

CC(CN)Cc1ccc(C(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.50
SLC6A2 P23975 2/20 0.42
SLC6A3 Q01959 1/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
EPHX1 P07099 1/20 0.40
ACACB O00763 2/20 0.39
PYCR1 P32322 1/20 0.38
COPS5 Q92905 1/20 0.38
TAAR1 Q96RJ0 2/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20160614 0.85 TAAR1 (0.54) SLC6A2SLC6A3ESR1ESR2EPHX1
SCHEMBL232629 0.83 SLC6A2 (0.63) IDO1SLC6A2SLC6A3ACACBTAAR1
SCHEMBL23466724 0.81 IDO1 (0.48) IDO1SLC6A2SLC6A3ESR1ESR2
Hydrochloric Acid SCHEMBL1695433 0.81 SLC6A2 (0.61) IDO1SLC6A2SLC6A3ACACBTAAR1
SCHEMBL10665841 0.80 TAAR1 (0.48) IDO1SLC6A2SLC6A3ACACBTAAR1
SCHEMBL18570895 0.80 IDO1 (0.47) IDO1SLC6A2SLC6A3ESR1ESR2
SCHEMBL23047509 0.80 TAAR1 (0.48) SLC6A2SLC6A3ACACBTAAR1
SCHEMBL20610522 0.78 ESR1 (0.45) IDO1ESR1ESR2EPHX1ACACB
SCHEMBL17393790 0.78 TAAR1 (0.46) IDO1EPHX1ACACBPYCR1TAAR1
SCHEMBL1219827 0.78 ESR1 (0.45) IDO1ESR1ESR2EPHX1ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0006992-A1 3-(p-Isopropyl-phenyl)-2-methyl-n-propyl amines, fungicides containing these compounds, a method for the preparation of said compounds and a method for combating fungi by using said compounds BASF Aktiengesellschaft (DE) 1980-01-23 EP claimed
EP-2376485-B1 PYRAZINE DERIVATIVES USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMA (US) 2017-12-06 EP disclosed
US-5650417-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-07-22 US disclosed
WO-1996037473-A1 SUBSTITUTED 2,3-CYCLOALKENOPYRIDINES, PROCESS FOR PREPARING THE SAME, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1996-11-28 WO disclosed
EP-0719255-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
WO-1995007890-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed
EP-0006992-A1 3-(p-Isopropyl-phenyl)-2-methyl-n-propyl amines, fungicides containing these compounds, a method for the preparation of said compounds and a method for combating fungi by using said compounds BASF Aktiengesellschaft (DE) 1980-01-23 EP disclosed
EP-0006992-A1 3-(p-Isopropyl-phenyl)-2-methyl-n-propyl amines, fungicides containing these compounds, a method for the preparation of said compounds and a method for combating fungi by using said compounds BASF Aktiengesellschaft (DE) 1980-01-23 EP disclosed
EP-0006992-A1 3-(p-Isopropyl-phenyl)-2-methyl-n-propyl amines, fungicides containing these compounds, a method for the preparation of said compounds and a method for combating fungi by using said compounds BASF Aktiengesellschaft (DE) 1980-01-23 EP disclosed