Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056971 | 0.81 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2ALDH1A1NPSR1HPGD | |
| SCHEMBL10611492 | 0.80 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2ALDH1A1NPSR1HPGD | |
| SCHEMBL8744354 | 0.79 | SMN1; SMN2 (0.50) | KMT2ASMN1; SMN2ALDH1A1NPSR1HPGD | |
| SCHEMBL2341926 | 0.75 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2ALDH1A1NPSR1GAA | |
| SCHEMBL11332992 | 0.75 | SMN1; SMN2 (0.49) | KMT2ASMN1; SMN2ALDH1A1NPSR1HPGD | |
| SCHEMBL9052728 | 0.74 | KMT2A (0.39) | KMT2ASMN1; SMN2ALDH1A1NPSR1HPGD | |
| SCHEMBL7849587 | 0.72 | KMT2A (0.50) | KMT2ASMN1; SMN2ALDH1A1NPSR1HPGD | |
| SCHEMBL17902 | 0.71 | KMT2A (0.53) | KMT2ASMN1; SMN2ALDH1A1NPSR1HPGD | |
| SCHEMBL5510580 | 0.71 | KMT2A (0.49) | KMT2ASMN1; SMN2ALDH1A1NPSR1HPGD | |
| SCHEMBL26136014 | 0.71 | KMT2A (0.45) | KMT2ASMN1; SMN2ALDH1A1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |