SCHEMBL8840665

SCHEMBL8840665

CCOC(=O)N(CC)Oc1ccc(Cn2cccn2)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
TSHR P16473 1/20 0.42
GAA P10253 4/20 0.40
MAPT P10636 3/20 0.40
USP2 O75604 1/20 0.40
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KLKB1 P03952 2/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KAT7 O95251 2/20 0.38
KAT6A Q92794 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8840688 0.92 HDAC1 (0.46) HTTHDAC1HDAC6KMT2AMEN1
SCHEMBL8840676 0.84 HDAC1 (0.48) HTTHDAC1HDAC6KMT2AMEN1
SCHEMBL8840670 0.83 SMN1; SMN2 (0.41) HTTGAAMAPTLMNASMN1; SMN2
SCHEMBL8383297 0.81 ADRB3 (0.48) HTTHDAC1HDAC6KMT2AMEN1
SCHEMBL7634000 0.76 TSHR (0.44) HTTHDAC1HDAC6KMT2AMEN1
SCHEMBL7635767 0.76 HTT (0.46) HTTHDAC1HDAC6KMT2AMEN1
SCHEMBL8840710 0.75 HDAC1 (0.51) HTTHDAC1HDAC6KMT2AMEN1
SCHEMBL8384881 0.74 GAA (0.46) HTTHDAC1HDAC6KMT2AMEN1
SCHEMBL8380240 0.72 GAA (0.50) HTTHDAC1HDAC6KMT2AMEN1
SCHEMBL7630025 0.72 HDAC1 (0.45) HTTHDAC1HDAC6KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5684022-A ANTIFERTILITY AGENT PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-04 US disclosed