Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 2/20 | 0.47 |
| ▸ | THPO | P40225 | 2/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840781 | 1.00 | AKR1B1 (0.53) | AKR1B1MCL1POLBTSHRNFKB1 | |
| SCHEMBL8840928 | 1.00 | AKR1B1 (0.53) | AKR1B1MCL1POLBTSHRNFKB1 | |
| SCHEMBL502877 | 0.85 | AKR1B1 (0.58) | AKR1B1MCL1POLBTSHRNFKB1 | |
| SCHEMBL8645186 | 0.83 | AKR1B1 (0.48) | AKR1B1MCL1POLBTSHRNFKB1 | |
| Alcohol SCHEMBL22343921 | 0.77 | AKR1B1 (0.50) | AKR1B1MCL1POLBTSHRNFKB1 | |
| SCHEMBL13283788 | 0.76 | AKR1B1 (0.48) | AKR1B1MCL1POLBTSHRNFKB1 | |
| SCHEMBL3833719 | 0.74 | AKR1B1 (0.47) | AKR1B1MCL1POLBTSHRNFKB1 | |
| SCHEMBL28763270 | 0.74 | AKR1B1 (0.47) | AKR1B1MCL1POLBTSHRNFKB1 | |
| SCHEMBL31038253 | 0.74 | AKR1B1 (0.47) | AKR1B1MCL1POLBTSHRNFKB1 | |
| SCHEMBL8840822 | 0.74 | F13A1 (0.61) | TSHRNFKB1LMNAPMP22MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637669-A | THERMOSETTING RESIN; LIQUID CRYSTALLINE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0670856-A1 | THERMOSETTABLE COMPOSITION CONTAINING MESOGENIC MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994012556-A2 | THERMOSETTABLE COMPOSITION CONTAINING DISCOTIC MESOGENIC MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1994-06-09 | — | — | WO | disclosed |