Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1301661 | 0.98 | TSHR (0.65) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL13474797 | 0.98 | TSHR (0.65) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL820598 | 0.98 | TSHR (0.65) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL10441178 | 0.95 | TSHR (0.68) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL10584770 | 0.93 | TSHR (0.73) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL15923909 | 0.93 | TSHR (0.73) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL678273 | 0.93 | TSHR (0.73) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL15593792 | 0.93 | TSHR (0.73) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL8386491 | 0.93 | TSHR (0.73) | TSHRFAAHTRPV1MEN1THRB | |
| SCHEMBL19775094 | 0.93 | TSHR (0.73) | TSHRFAAHTRPV1MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9067315-A | — | — | None | — | — | JP | disclosed |
| US-8420068-B2 | Polymer-based compositions and conjugates of antimicrobial agents | NEKTAR THERAPEUTICS (US) | 2013-04-16 | — | — | US | disclosed |
| JP-H0967315-A | PRODUCTION 4-ACYLOXY-1-BUTANAL | KURARAY CO LTD | 1997-03-11 | — | — | JP | disclosed |
| EP-0357372-A2 | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-03-07 | — | — | EP | disclosed |