Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312400 | 0.91 | CYSLTR1 (0.55) | ALDH1A1MAPTMEN1NPC1RAB9A | |
| SCHEMBL8309648 | 0.90 | CYSLTR1 (0.54) | ALDH1A1MAPTMEN1NPC1RAB9A | |
| SCHEMBL8309656 | 0.90 | CYSLTR1 (0.54) | ALDH1A1MAPTMEN1NPC1RAB9A | |
| SCHEMBL7598790 | 0.90 | CYSLTR1 (0.56) | ALOX5CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL8309652 | 0.90 | NPC1 (0.47) | ALDH1A1MAPTMEN1NPC1RAB9A | |
| SCHEMBL8842339 | 0.87 | CYSLTR1 (0.53) | ALOX5CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL7607544 | 0.82 | MAPT (0.60) | ALDH1A1MAPTMEN1NPC1RAB9A | |
| SCHEMBL7599588 | 0.82 | CYSLTR1 (0.62) | ALOX5CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL7608634 | 0.81 | MAPT (0.59) | ALDH1A1MAPTMEN1NPC1RAB9A | |
| SCHEMBL7608640 | 0.80 | CYP1A2 (0.55) | ALDH1A1MAPTMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668150-A | ANTIALLERGY, ANTIINFLAMMATORY | ABBOTT LABORATORIES (US) | 1997-09-16 | — | — | US | disclosed |