Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.57 |
| ▸ | EBP | Q15125 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.57 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770234 | 0.89 | ESR1 (0.49) | ESR1EBPKMT2ACHRM2ADRA2A | |
| SCHEMBL8613896 | 0.82 | ESR1 (0.83) | ESR1EBPKMT2ACHRM2ADRA2A | |
| SCHEMBL8612333 | 0.82 | ESR1 (0.83) | ESR1EBPKMT2ACHRM2ADRA2A | |
| SCHEMBL8613900 | 0.82 | ESR1 (0.83) | ESR1EBPKMT2ACHRM2ADRA2A | |
| SCHEMBL8612902 | 0.82 | ESR1 (0.83) | ESR1EBPKMT2ACHRM2ADRA2A | |
| SCHEMBL8612329 | 0.82 | ESR1 (0.83) | ESR1EBPKMT2ACHRM2ADRA2A | |
| SCHEMBL8612511 | 0.82 | ESR1 (0.83) | ESR1EBPKMT2ACHRM2ADRA2A | |
| SCHEMBL8613390 | 0.82 | ESR1 (0.83) | ESR1EBPKMT2ACHRM2ADRA2A | |
| SCHEMBL8613392 | 0.82 | ESR1 (0.83) | ESR1EBPKMT2ACHRM2ADRA2A | |
| SCHEMBL8612323 | 0.82 | ESR1 (0.83) | ESR1EBPKMT2ACHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691384-A | Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-25 | — | — | US | disclosed |