Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.32 |
| ▸ | CCKBR | P32239 | 2/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842822 | 0.93 | — | — | |
| SCHEMBL8843400 | 0.93 | — | — | |
| SCHEMBL8842764 | 0.93 | SCN9A (0.33) | SCN9ACCKBRCCKARMEN1ALDH1A1 | |
| SCHEMBL8842956 | 0.92 | MDM2 (0.32) | MEN1ALDH1A1LMNAGLAPOLB | |
| SCHEMBL7323240 | 0.92 | SCN9A (0.32) | SCN9ACCKBRCCKARMEN1ALDH1A1 | |
| SCHEMBL7334474 | 0.87 | SCN9A (0.33) | SCN9ACCKBRCCKARMEN1ALDH1A1 | |
| SCHEMBL8843026 | 0.86 | MEN1 (0.31) | MEN1ALDH1A1LMNAGLAPOLB | |
| SCHEMBL8843000 | 0.85 | MEN1 (0.32) | MEN1ALDH1A1LMNAGLAPOLB | |
| SCHEMBL7329748 | 0.84 | — | — | |
| SCHEMBL7329444 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |