Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | TTPA | P49638 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14168733 | 0.88 | MEN1 (0.64) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8376060 | 0.88 | MEN1 (0.64) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9656784 | 0.87 | MEN1 (0.62) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL10724913 | 0.87 | MEN1 (0.62) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL10724905 | 0.87 | MEN1 (0.62) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL11706067 | 0.86 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL11705132 | 0.86 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL11706578 | 0.86 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8377650 | 0.86 | MEN1 (0.67) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8601254 | 0.85 | MEN1 (0.66) | MEN1KMT2APDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663389-A | 3,4-Dihydro-2-iodomethyl-2,5,7,8-tetramethyl-2H-1-benzopyrans | ALFA WASSERMANN S.P.A. (IT) | 1997-09-02 | — | — | US | claimed |
| EP-0737681-A1 | 3,4-Dihydro-2-iodomethyl-2,5,7,8-tetramethyl-2H-1-benzopyrans | ALFA WASSERMANN S.p.A. (IT) | 1996-10-16 | — | — | EP | claimed |
| EP-0737681-A1 | 3,4-Dihydro-2-iodomethyl-2,5,7,8-tetramethyl-2H-1-benzopyrans | ALFA WASSERMANN S.p.A. (IT) | 1996-10-16 | — | — | EP | disclosed |